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Description

AG442005: α-D-Gal-Butyl-Carboxylic AcidC11H20O8 280. 27 An D galactose ligand equipped with a terminal carboxylic acid through a short butyl spacer. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on proteins and peptides to form stable amide bonds. This compound provides an anomeric galactose building block for glycoconjugate synthesis, glycomimetic research, and the construction

which can be removed under acidic conditions to reveal the free amine for conjugation

β-D-(Gal(Ac)4β1-4Glc(Ac)3)-O-(CH2)2-N3

producing high-avidity binding that substantially exceeds the affinity of monovalent GalNAc ligands and closely mimics the geometry of clinically validated Tri-GalNAc targeting moieties used in approved GalNAc-siRNA therapeutics

This compound enables the construction of lysosome-targeted therapeutics and research tools that exploit the mannose-6-phosphate receptor (M6PR)

33 / A β-D-N-acetylglucosamine (GlcNAcβ) ligand equipped with a thiol-functionalized linker through a short ethyl spacer

kojibiose hydrolase

The biotin tag enables immobilization on streptavidin/neutravidin-coated platforms

particularly the human-adapted strains that preferentially recognize α2-6-linked sialic acids

methyl ester

22 / An α-L-rhamnose ligand equipped with an amine-functionalized linker through a short ethyl spacer

27 / An α-D-galactose ligand equipped with a terminal carboxylic acid through a short butyl spacer

β-D-Glc-Pr-N3

Exchange/Return Notes